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The author is not a physician. The content on this website does not, and is not intended to constitute medical advice. It should not be relied upon when making medical decisions. It is not intended as a substitute for advice from your physician or other healthcare provider.

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Silibinin (Liver? I hardly knew her!)

Category: Drugs
Posted on: April 3, 2008 9:00 AM, by Molecule of the Day

As Uncle Al mentioned, many antioxidants are ill-tolerated by the liver. However, it loves one antioxidant: silibinin.


Silibinin, found in Blessed Milk Thistle, is actually hepatoprotective - to the extent that it's used in toxic mushroom poisoning in hospitals in Europe!

Comments

Until we get you up to speed with posting the links to ChemSpider I'll do them for you...this one is here:

http://www.chemspider.com/Chemical-Structure.29263.html

Posted by: ChemSpiderMan | April 3, 2008 12:23 PM

Flavonoids overall are cryptoestrogens. Pre-pubescent males who eat lots of soy don't become porn stars (dosed in the womb by Mom liking Hamburger Helper or tofu, etc.). Silibinin is an effective
anti-androgen as therapy for prostate cancer. Cultural flavonoids in food lower the incidence of prostate cancer in a population. There is that small side effect...

http://www.cazv.cz/UserFiles/File/46-17-23.pdf
Estrogenic effects of silymarin in ovariectomized rats
Look at the dose/kg not at the dose/rat, then scale to a 25 kg child.

Posted by: Uncle Al | April 3, 2008 1:51 PM

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