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Ed lives in London and works at Cancer Research UK. This blog is his attempt to make science interesting to everyone by beating jargon, confusion and elitism with the stick of good writing. Almost all posts will be proper articles that discuss peer-reviewed research, written from the original papers. Ed is an award-winning science writer and has freelanced for Nature, New Scientist and the Economist. He finds writing about himself in the third person strange and unsettling.


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May 10, 2008

How Big Brother keeps us honest

Category: AltruismCooperationPsychology

Revisited.jpg Imagine that you're walking along a quiet street and you see a wallet lying on the pavement. Would you take it? Now imagine a slightly different situation - the wallet has a red circle drawn around it. While many people would be tempted in the first scenario, almost no one would touch the wallet in the second. The key difference is that the lone wallet was most likely dropped accidentally by a passer-by buy the encircled wallet was clearly placed and marked by someone, who may well still be watching. And there is nothing that keeps people more honest than the presence of a watchman.

Blogging on Peer-Reviewed Research Social experiments like these are of great interest to biologists because they tell us more about the nature of selfishness and altruism. In recent years, selfishness has become something of a biological buzzword and many influential writers have cast living things as self-serving vessels acting for the benefit of their genes. In this harsh light, individuals co-operate with each other only if they reap a personal reward.

Wallet.jpgBut some acts of altruism, particularly human ones, are harder to explain. We are often kind and generous to others, even if they are unrelated (and so share no genes) or are unlikely to ever repay the good deed. Is this true selflessness, or is there something else going on? One theory is that such selfless acts do provide benefits - they raise the reputation of the do-gooder in the eyes of their peers. Even selfish people can act selflessly when their reputation is on the line.

Lab experiments have shown that people co-operate more strongly if they know they are being watched. But Melissa Bateson and colleagues at the University of Newcastle have shown just how honest people become when they feel that Big Brother is watching them, using a cunning experiment in a more natural environment. Rather than artificial confines of a lab, they chose to run a simple test on the unwitting members of their university's Division of Psychology in their own coffee room.

May 9, 2008

Rats succumb to peer pressure too

Category: Animal behaviourAnimalsMammalsRats

Blogging on Peer-Reviewed Research
This week's New Scientist includes a short piece from me about conformist rats. brownrat.jpg
Until now, only humans and chimps were known to succumb to peer pressure, to the extent that we often ignore our own experiences based on the preferences of others. But a new study in brown rats shows that these rodents are similarly prone to following the Joneses. They can even be persuaded to choose a piece of food that they know makes them sick if they smell it on the breath of a 'demonstrator' rat.

May 8, 2008

March of the locusts - individuals start moving to avoid cannibals

Category: Animal behaviourAnimal locomotionAnimalsInsectsInvertebrates

Blogging on Peer-Reviewed Research A tenth of the planet's population occasionally suffers through devastating famines because small insects fear being bitten in the bum. That's the astonishing message from a new study of one of mankind's greatest pests - the desert locust.

DesertLocust.jpg Swarms can stretch for several hundred square kilometres and each of these harbours up to 80 million hungry sets of mandibles that eat their own body weight in food every day. These plagues are unpredictable but they only form when locust populations reach some sort of critical mass. Desert locusts are two insects for the price of one; at a crowded tipping point, they transform from loners (which are green or brown) into more sociable forms that are red or yellow and prone to swarming.

With much of Asia's and Africa's food supplies at stake, researchers are keen to discover what prompts the transformation from disorders groups of solitary locusts to highly organised marches of sociable ones. Two years ago, an international team led by Stephen Simpson showed that this switch is very rapid. Once groups reach a certain density, individuals that were previously doing their own thing started stepping in  line with their neighbours.

This sudden coordination is an important step in the genesis of a swarm, but the researchers had still to uncover why the locusts aligned so neatly. Now, working with the same group, Sepideh Bazazi at the University of Oxford has found part of the answer - they to march to avoid getting cannibalised by other locusts behind them. All the individuals in a dense group are after the same things - protein, salt and the like. If one stops moving, it risks acting as a source of these nutrients for others behind it. For locust groups, life is about moving with the crowd, or being eaten by it.

May 6, 2008

Cuckoos mimic hawks to fool small birds

Category: Animal behaviourAnimalsBirdsMimicry

Blogging on Peer-Reviewed ResearchCuckoos are some of nature's most familiar conmen. Several species of this large family are murderous slackers, who shun their own parental responsibilities by deceiving other birds into caring for their chicks. In the process, they destroy the eggs of the unwitting adopted family to ensure that their own chick gets undivided attention. But this is not the only way that cuckoos fool other birds - they also mimic hawks.

Reed_warbler_cuckoo.jpg The resemblance between cuckoos and hawks (particularly sparrowhawks) has been noted for millennia. Both birds have long bodies, wings and tails and their paler, striped undersides contrast against a darker grey or brown backs. The resemblance is uncanny enough that Pliny believed that cuckoos disappeared from Europe in the winter by transforming themselves into hawks, a theory that Aristotle rightly dismissed on the grounds that cuckoos lacked the formidable talons and curved beak of hawks.

Hawks and cuckoos belong to two very different families of birds, so why do they look so similar? Non-parasitic cuckoos (and indeed, not all cuckoos leech off the parenting skills of other birds) provide an important clue, for they look much less than hawks than parasitic species. There are two possible explanations for this similarity.

The first is that both groups have independently evolved the same physical traits for the same reasons - a process called convergent evolution. Neither bird wants to be seen by potential prey or hosts. As they perch in twigs and branches, having a darker back makes them harder to spot, and bars on the underside help to break up their outline. Their body shape helps them to make a controlled glide, which sparrowhawks use to launch surprise attacks, and cuckoos use to sneak up on a targeted nest.

Alternatively, the cuckoos could be actively mimicking the hawks. The disguise could fool the cuckoos' predators. That's useful for them as they aren't particularly powerful or agile birds and they spend a lot of time on exposed perches, keeping an eye on the nests of potential victims. They could also fool potential parents. The host birds either run away, which gives the cuckoo free passage into their nests, or they mob the supposed predator en masse, which gives away the location of their precious nests. So which theory is right?

May 5, 2008

Fungi transform depleted uranium into chemically stable minerals

Category: EnvironmentFungi

Blogging on Peer-Reviewed ResearchThe countryside around Iraq and the Balkans are still suffering from the ravages of wars fought in the 1990s. The environment is littered with the potentially dangerous remnants of military weapons - depleted uranium.

Fungiuranium.jpgDepleted uranium is what's left over after 'enrichment', when uranium-235 is separated from natural uranium. This isotope is suitable for nuclear reactors and weapons, and the remainder consists of uranium-238, a less radioactive isotope with a longer half-life. This "depleted uranium" is valued by the military for its high density and is often combined with titanium to produce an alloy used in both armour-piercing weapons and defensive plating.

But penetrating rounds aren't the only potential threat to human health posed by depleted uranium. The substance is still radioactive, can cause heavy metal poisoning and burn spontaneously on impact to produce aerosols of uranium compounds. These potential risks have been downplayed by many reports but they make the use of depleted uranium in munitions highly controversial, especially when locals have to deal with traces that litter the landscape after battle ceases.

Now, a new study shows that very unlikely allies may be helping to clean up these remains. Marina Fomina from the University of Dundee found that several species of fungi can not only thrive on depleted uranium, but also convert it into stable minerals.

May 4, 2008

Making sense of obesity genes

Category: GeneticsMedicine & healthObesity

Blogging on Peer-Reviewed ResearchThis is a quick follow-up to my other post on fat cells, which as it happens, isn't the only obesity-related story out today. Another paper found a common genetic variant that increases the risk of obesity in its carriers.

A huge team of researchers scoured the genomes of almost 17,000 European people for genetic variations that are linked to obesity. Until now, only one has been found and it sits within a gene called FTO. This new study confirmed that FTO variants have the strongest association with obesity, but in the runner-up position is another variant near a gene called melanocortin-4 receptor or MC4R.

Fat cell number is set in childhood and stays constant in adulthood

Category: Medicine & healthObesity

Blogging on Peer-Reviewed ResearchAs fat people have an abundance of fat tissue, the natural assumption is that fat people have more fat cells, or 'adipocytes'. That's only part of the story - it turns out that overweight and obese people not only have a surplus of fat cells, they have larger ones too.

Adipocytes.jpgThe idea of these 'fatter fat cells' has been around since the 1970s. But their importance has been dramatically highlighted by a new study, which shows that the number of fat cells in both thin and obese people is more or less set during childhood and adolescence. During adulthood, about 8% of fat cells die every year only to be replaced by new ones. As a result, adults have a constant number of fat cells, even those who lose masses of weight. Instead, it's changes in the volume of fat cells that causes body weight to rise and fall.

Kirsty Spalding from the Karolinska Institute in Sweden, together with a large team of international researchers, uncovered several lines of evidence to support these conclusions. Her study is a fascinating mix of cell counting, stomach surgery, radioactive Cold War fallout and a rather surprising use for carbon-dating.

May 3, 2008

Dogs and devils - the rise of the contagious cancers

Category: AnimalsEvolutionMammalsMedicine & healthParasites

I'm away for the weekend so I thought that I'd repost an article from the old Wordpress blog. This is actually the first ever article I wrote for Not Exactly Rocket Science and I've updated it slightly to take more recent findings into account. I'm considering doing these reposts every Saturday, but let me know whether you're keen on the idea.

Blogging on Peer-Reviewed ResearchCancer cells are, for all intents and purposes, immortal. Having broken free of the rules and strictures that govern other cells, they are free to grow and divide as they please. In a short space of time, a lone cancer cell can form a mass of identical clones - a tumour. Often, these grow and spread quickly at the expense of their host who usually ends up dying, taking the tumour with it. But there is one way a cancer could escape this fate and carry on its selfish reproduction - by finding another host. It could become contagious.

Tasmanian_Devil.jpgIn humans, cancers are definitely not contagious. You can't catch cancer from someone who has it; at most, you can inherit a higher risk of developing cancer, because of faulty genes passed on from your parents. But we now know of two animal cancers that are exceptions to this rule - one has spread all over the world from a single individual and the other threatens to exterminate an entire species.

In 2006, Australian researchers Anne-Marie Pearse and Kate Swift found that a facial cancer plaguing the local Tasmanian devils was caused by contagious cancers. The condition, known as devil facial tumour disease, is spread when an infected devil bites another. The devils' boisterous temperaments and their propensity for squabbling over carcasses mean that such bites are common. Once infected, the animals develop grotesque tumours that stop them from feeding properly, and they usually die of starvation within six months. As a result, the cancer is decimating the already small population.

The second type of contagious cancer is far more widespread and affects far more familiar hosts - domestic dogs. The disease in question is called canine transmissible venereal tumour (CTVT), or Sticker's sarcoma and it's a case of a cancer cell evolving into a global parasite.

May 1, 2008

Sexy jumping spiders court females with ultraviolet patches

Category: Animal behaviourAnimal communicationAnimalsInvertebrates

Blogging on Peer-Reviewed Research Ultraviolet (UV) radiation lies beyond the violet end of the rainbow. Our eyes aren't equipped to see it and its presence only becomes visually apparent when enough of it hits our skin and causes a painful, red patch - a sunburn. But not all animals have eyes that are so ill-equipped. The females of the jumping spider Phintella vittata not only see UV light, they also find it sexy.

Phintella.jpg UV light may be invisible to us but many animals can see it and use it to communicate. Sometimes, this is deliberate, as in the case of blue tits using UV patches to seduce females. It can also be inadvertent and downright unfortunate, as in the case of voles that give away their position to hovering kestrels through the UV reflections from their urine. Even though UV-based messages are widespread, those of the jumping spiders are unique, for they use a specific type of ultraviolet light called UVB.

The UV-sensitive cells in animals that can detect ultraviolet light almost always respond most strongly to UVA, the type that lies closest to violet and has the longest wavelengths. It's usually been assumed that even though ultraviolet vision is very common among animals, none of them can see into the UVB range. Until now, only three exceptions have been recently found - a species of thrip (a tiny insect) and two species of poison-arrow frogs. And all of these detect UVB so that they can avoid it.

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