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Doc Bushwell is a biochemist and a minion fugitive thrall of the dark lords of Big Pharma; Jim is a college professor with a fondness for running shoes and drumsticks; and Kevin is a freelance writer who focuses on the science of athletics performance. Read our interview with Science Blogs.

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May 12, 2008

OKC's weight-loss campaign, and ironic uses of "irony"

Category: Health and Society

Three months ago, I mentioned that the mayor of perennially zaftig Oklahoma City, having lost 38 pounds in 10 months himself, had launched an initiative aimed at getting locals to shed excess weight. By late April, over 17,700 official participants in Cornett's program had lost a collective 68,700 pounds over 16 weeks, about four pounds per person and roughly a pound a month. The ultimate goal: one million collective pounds shed.

Clearly, the numbers are less important than the overall promotion of lifestyle changes that include healthful weight loss as onely one benefit. The site Cornett launched is hardly a "let's-start-starving-you-lardballs!" production; it includes all sorts of information about exercise, nutrition, behavioral modification and so on.

As the wire story explains, fast-food megachain Taco Bell, having launched a new low-fat "Fresco Menu" in December, contacted Cornett after learning of his brainchild and his concomitant fears that fast-food restaurants would balk at it. Company reps told Cornett that once the number of dropped pounds of program participants reaches 100,000, everyone in OKC will be entitled to a free low-fat taco from the recently launched menu. And, save for the fact that Taco Bell's food (in my opinion) tastes like shit warmed over, they all lived happily ever after.

Well, not exactly.

OKC's weight-loss campaign, and ironic uses of "irony"

Category: Health and Society

Three months ago, I mentioned that the mayor of perennially zaftig Oklahoma City, having lost 38 pounds in 10 months himself, had launched an initiative aimed at getting locals to shed excess weight. By late April, over 17,700 official participants in Cornett's program had lost a collective 68,700 pounds over 16 weeks, about four pounds per person and roughly a pound a month. The ultimate goal: one million collective pounds shed.

Clearly, the numbers are less important than the overall promotion of lifestyle changes that include healthful weight loss as onely one benefit. The site Cornett launched is hardly a "let's-start-starving-you-lardballs!" production; it includes all sorts of information about exercise, nutrition, behavioral modification and so on.

As the wire story explains, fast-food megachain Taco Bell, having launched a new low-fat "Fresco Menu" in December, contacted Cornett after learning of his brainchild and his concomitant fears that fast-food restaurants would balk at it. Company reps told Cornett that once the number of dropped pounds of program participants reaches 100,000, everyone in OKC will be entitled to a free low-fat taco from the recently launched menu. And, save for the fact that Taco Bell's food (in my opinion) tastes like shit warmed over, they all lived happily ever after.

Well, not exactly.

May 11, 2008

Hiassen on why Obama:Wright =/= McCain:Falwell, Hagee et al.

Category: Fun with Politics

Carl Hiaasen writes in his Miami Herald column today about Sen. Barack Obaba's association with the Rev. Jeremiah Wright, a yammering jackass who happens to be African-American but whose chief characteristic is his religious lunacy, a destructive influence which -- like alcoholism, AIDS, poverty, and other afflictions nearly as devastating and corrupt as a faith-based world view -- is color-blind.

Hiassen notes a very important distinction between Obama's relationship with Wright and McCain's (not to mention various other Republican notables') pandering to conservative Christabouts:

"McCain's bonding with Rev. Falwell remains harder to comprehend than Obama's relationship with Rev. Wright, which began before Obama's political career. Rev. Wright was Obama's hometown pastor in Chicago; not a national TV personality whose endorsement might help get him elected someday."

Spot on. McCain has a long history of symbolically fellating anyone whose influence might earn him votes, which is doubly troubling in that it not only speaks to McCain's mentality and character but also highlights how fucked up this country has to be to render squint-eyed, knee-walking shitbags like James Dobson and the not-late-enough Jerry Falwell -- who would be nothing more than cartoon villains in most any other advanced society -- people worth sucking up to. McCain claims to have balls whenever he invokes his POW days and the Iraq war, but if he had any real sack, and more importantly a concern for America's well-being, he's distance himself from these bloated old delusion-mongering pricks and rely on his strength as a leader to earn him a seat in the White House.

Florida, vanity, and lying healthcare dispensers

Category: The New Woo Revue

If there's one part of the country that may be as obsessed with its collective personal appearance as Los Angeles, it's Florida -- specifically its larger cities and metropolitan areas, especially those in the state's southern coastal areas: Miami-Fort Lauderdale-West Palm Beach, Tampa-St, Petersburg, Naples, Fort Myers, and others.

In L.A., people at least have the excuse of needing to look New and Improved owing to anticipated, incipient, or extant acting careers. In Florida people just want to look good for the hell of it, and more specifically don't want to look old even though the median age is (reaching into my ass here) about 87.3.

I live in the Sarasota-Bradenton mini-coglomerate, which numbers about 650,000 people, among them Stephen King, Paul Reubens (a.k.a. Pee Wee Herman), Jerry Springer, and Martina Navratilova. It's not the sprawling hell that Broward County, where I held my first Florida address, has become, and it retains a more of an "old Florida" feel than strip-mall- and golf-course-covered South Florida does. But make no mistake -- it has its fair share of eight-lane thoroughfares, magnificently inconsiderate drivers, and ugly condominiums, with the influx of humanity trickling off recently as a result not of carefully managed growth but of a cratering housing market.

Getting back to the main idea here, plastic surgery and its derivatives are more than alive and well -- they're thundering around town, priapic and beaming ever prepared to give your wallet a nice reaming while returning nothing of value. And some of those derivatives are comically, gloriously dishonest.

May 10, 2008

Recipes for reaching out

Category: The Running Ape

Alison Wade is not only a tireless and largely unheralded member of the national distance-running media, but a genuine Idea Person too. If you don't know the background on Ryan Shay or Jenny Crain, follow the appropriate links below.

 

We are pleased to announce the publication of The Runner's Cookbook: Winning Recipes from Some of the World's Best Athletes, a fundraising cookbook for Jenny Crain and Ryan Shay.

The Runner's Cookbook features 100 recipes from 90+ contributors, including Joan Benoit Samuelson, Sebastian Coe, Shalane Flanagan, Adam and Kara Goucher, Ryan and Sara Hall, Deena Kastor, Craig Mottram, Dathan Ritzenhein, Khadevis Robinson, Alan Webb, and many others. All of the proceeds from the sales of this book will be donated to the Ryan Shay Memorial Fund and the Jenny Crain "Make It Happen" Fund.

Any corrections, updates, or information about this project will be added to this web site as they come up. If you have any trouble ordering this book, or with the quality of the product you receive, please let us know. We can't necessarily fix the problem, but we'd like to be aware of it, so we can do our best.

Buy the Cookbook | About Ryan Shay and Jenny Crain | Corrections | About the Editor | Contact Us

 
   

Obama clears important hurdle in Oregon

Category: Hootworthy

That may be overstating things, as the video reveals. But given the muddled political picture at the moment (a tableau undoubtedly made all the more obscure by my own apathy), the senator's showing up at the Oregon Twilight Track and Field Classic last night seems as good a reason as any to support him, especially now that he basically can't lose the Democratic nomination and is capable of beating John McCain in the general election.

I was disappointed that the athletic-looking Obama made no attempt to actually hurdle the hurdle. More interesting would be a video of McCain attempting to clear 15 feet in the pole vault, preferably with no mat.

May 9, 2008

I'm shaking, all right

Category: Society Gone Bananas

Creationists, as blind to the tangible and visible realities of today as they are to the scientific evidence describing how this world and its inhabitants turned out they way they have, are fond of complaining that no unguided process could have created so many forms of life perfectly suited for their niches, creatures efficient and elegant in every way.

If you need to be convinced that evolution is anything but flawless, look no further than Quiver Full Ministry. The goal of this ministry is to make sure people copulate themselves senseless (a fairly quick and straightforward process for adherents) while strictly shunning any and all forms of birth control.

Then there's the usual trash about humanism being bad (a curious yet common Christian assertion that seems only slightly removed from complaining about mercy or compassion), the furious misinterpretation of the First Amendment by secular assholes who just won't accept America's Bibical, Judeo-Christian roots, all sorts of slimy propaganda about the evils of contraception, and various other other solecisms, myth-making, and no-holds-barred cracked-cross bullshit.

Intelligence may not be everything in terms of survival value, but it's the one factor that most sharply distinguishes us from various literal herds. So, given that the stupidest and most hapless members Homo sapiens are -- especially in advanced societies -- almost preternaturally eager to procreate until pieces and parts finally and mercifully wear out, it is safe to say that evolution is anything but a process involving a foregone conclusion or guaranteed improvements on models past.

If this sort of thing continues, it won't be long before people look and sound like larger verson of the Tweedlebugs of Sesame Street fame, chittering madly about nothing between coupling sessions and displaying perfectly bulbous eyes on gently waving stalks, too oblivious to reality to be anything but blissful, pregnant, and covered in shit-smeared diapers and Gerber food.

May 7, 2008

Nasty fall in the World Champs steeplechase (not for the queasy)

Category: The Running Ape

The good news, right up front: Günther Weidlinger is alive, well and at the top of his game. The Austrian was second to Australia's Craig Mottram in the 10,000 meters on Sunday night at the Cardinal Invitational at Stanford, a meet which annually hosts some the most competitive springtime distance races in the world. Weidlinger, who knocked 42 seconds off his previous 10,000-meter best, is Austria's record holder in 1,500m (3:34.69), 5,000m (13:13:44), the 3,000m steeplechase (8:10.83) and the 10,000 (27:36.46).

What may be most remarkable is that Weidlinger ever got up after a horrible fall on the second lap of an early heat of the World Championships steeplechase last summer in Osaka. The steeple -- a 7 1/2-lap event that involves five 36-inch-high barriers, one of them including a water jump, on each lap -- a is a grueling event, even harder than it looks (and it looks plenty tough). I've seen people do faceplants into the water pit and I've seen them hook their feet on the barrier and come crashing to the track. But I've never seen anything like what happened to Weidlinger a little over 45 seconds into this video.

Fortunately, track and field remains, for the most part, a non-contact sport with a minimal risk of serious injury. So I wouldn't recommend screening this one at too many summer youth running camps.

Altared states: Bradfield gnashing his buttocks over gays again

Category: Spankin' the Crank

I admit that I disappoint myself by vacillating between topics that deal with interesting new developments in science and functionally illiterate bigoted hicks whose minds are under siege from a two-pronged demolition team, with an innate lack of cognitive wattage protruding from one side and lifelong religious indoctrination jutting out from the other. But when someone is as consistently malevolent, hypocritical, and laughable all at the same time as Nathan Bradfield is, it's fair to consistently maraud him. After all, as he'll tell you himself, he is the quintessential Christian, and folks who may not be convinced how akimbo the minds of these slap-happy ding-dongs have every reason to be as informed as possible.

Nathan is making a stupendously senseless complaint, one adored by wingnuts across the land: that calling people on their intolerance and unfair judgment invoked a double standard, because dammit, the person doing the calling is himself being intolerant and judgmental!

Most people can spot the flaws in this "logic." If I go on record as saying that blacks make poor cellists and am criticized by my employer, friends, or the media, few would be sympathetic to any pleas I might make about being targeted by hate speech or not being given the right to speak my mind. Yet this is exactly what the Bradfield errorbot does, over and over, and now he's waxing apoplectic about the travails of a University of Toledo pencil-pusher who wrote a wreck of a column for the Toledo Free Press that included this idiotic passage:

The vexing curiosities of sled dogs' metabolisms

Category: Bio-bizarre

The New York Times ran a piece yesterday about the biochemical anomalies of dogs who compete in the Iditarod, an 1,161-mile, eight- to fifteen-day sledding race across Alaska which is something of a companion event to the Tour de France in that it for a week or two it commands the interest of Americans in a sport they are generally content to ignore.

badasshuskies.jpg

Long-distance runners have two chief concerns. One is aerobic fitness. Competitors in events ranging from the 800 meters (which is considered roughly half-aerobic and half-anaerobic based on the relative contribution of different fueling pathways and fuel sources) all the way up to the multi-day events favored by the lovable nutjobs in the ultramarathon community have to be trained not only to transport more oxygen to the working muscles, which is accomplished chiefly by adaptations in cardiac muscle and increases in the number of red blood cells, but also to more efficiently utilize the oxygen that arrives at those muscles, which occurs through increases in mitochondrial density in muscle cells and other changes.

Second, true endurance athletes face an additional concern that 5K and 10K racers do not. Roughly speaking, even well-trained athletes -- whose bodies are better at storing glycogen, the polymer form of glucose and the primary fuel in aerobic exercise any more intense than walking, than those of sedentary people -- can only stock up on about 500 grams of glycogen (about 100 in liver and the rest in muscle). This is enough for about 20 miles of perambulation, give or take and varying as a function of individual athletes' efficiency. So while you don't have to be especially diligent about "carbo-loading" before a race lasting under an hour and a half or so, you cannot expect to perform at your best in a marathon without taking in some kind of carbohydrate, usually in drink or gel form for ease of digestibility, along the way.

As you might expect, humans' metabolic rates soar while they are taking part in exercise, and especially intense bouts lead to an elevated basal metabolic rate (BMR) for hours after the body comes to rest. I can recall numerous nights in which I lay in bed having raced a marathon twelve or more hours earlier, sweating and listening to my heart hammer along at 120 beats a minute, about three times as fast is it normally is when I'm lying around.

But the metabolisms of sled dogs who participate in the Iditarod pose a genuine and intriguing mystery. Notes Michael S. Davis, an associate professor of veterinary physiology at Oklahoma State University and an animal exercise researcher:

May 6, 2008

Why it's important to sanction anti-gay discrimination

Category: Spankin' the Crank

Truth be told, I can't come up with a single reason -- good or bad -- why misinterpreting the Constitution in such a way as to portray freedom from religion-driven harassment on the basis of sexual preference as "liberalism run amok" is at all meaningful or necessary. I cannot fathom why some people believe that it is not only acceptable but obligatory to fire employees for the manner in which they seek consensual sexual gratification on their own time.

Then again, either can the addled and animated pile of excrement dubbed Nathan Bradfield, who exemplifies perfectly why places such as Alabama more closely resemble Third World outposts housed within the continental U.S. than legitimate American states. Never one to be stopped by his own freewheeling hypocrisy or his dogged inability to offer consequentialist arguments, Nathan is now bleating about a situation in Ontario in which a sinner and her supporters in the Canadian government, which fined Christian Horizons $23,000 for firing a lesbian over lesbianism, are pulling a fast one:

May 5, 2008

Huge 10,000-meter American record for Flanagan

Category: The Running Ape

Last night at the Peyton Jordan Cardinal Invitational, held at Stanford University's Cobb Track and Angell Field, Shalane Flanagan, a native of Marblehead, Mass. and a UNC-Chapel Hill graduate, and New Zealand's Kimberly Smith put on a marvelous show in the marquee event, the women's 10,000 meters. It was Flanagan's first attempt at the distance; to date she has focused on the 1,500m, the 5,000m, and cross-country.

On Christmas night, I sat down with Flanagan's coach, John Cook, at the home of a mutual friend, and discussed Flanagan's inevitable move to the longest track distance. John asked me what I thought Shalane could run the 10,000 in. I said close to 30:30. He said, "That's what I think. 30:30, maybe 30:32."

That's cutting it close, but this is a guy who has forgotten more track than I and most observers will ever know.

At the gun, Flanagan and Smith, who headed into the affair as the Kiwi record-holder (31:20), wasted no time in establishing that the chase for Deena Kastor's American record of 30:50 was on. Led by pacesetter Rose Koskei of Kenya, Flanagan passed the halfway point in about 15:16, with Smith several meters in arrears and the rest of the field -- hardly a slouchy group -- strung out far behind.

By the 8K mark it was clear that Kastor's record would fall and fall hard, but Smith and Flanagan were engaged in a classic footrace. Smith generously took the point and kept the pair on 73-second laps, and with 200 meters left the outcome was nowhere near settled.

In the end Flanagan eased ahead and prevailed by just over a second, 30:34.49 - 30:35.52. In notching the fastest time in the word this year, she lopped a jaw-dropping 16 seconds off the standard Kastor set two years ago at the same meet; Smith lopped an improbable 45 seconds of her own New Zealand record and also nabbed the Oceania record, previously held by Benita Johnson of Australia (30:37.68).

Among many other great performances doomed to be forgotten from the start, Sally KIpyego of Texas Tech, the 2007 NCAA cross-country champion, destroyed her own NCAA record by 30 seconds by running 31:25.45.

Here are the last two laps of the race, courtesy of RunnerSPACE.

Not your parents' confessional booth

Category: Hootworthy

A friend and running-club teammate unearthed IveScrewedUp.com, a place set up by Flamingo Road Church where you can confess to sins great and small to an the online audience. This seems to be a serious endeavor -- although a lot of the postings are semi-coherent and border on the absurd, as a group they're just to plaintive to be made up on the spot. Mostly, it's a bunch of expulsions from people feeling guilty about lying, cheating, stealing, masturbating, fornicating, being gay, being racist, and other boilerplate solecisms and non-offenses, and seeking to resolve their inner conflicts about these matters by interfacing with supernatural morality administrators. It's a little sad to see so much misery in one spot, but it's interesting, and it's instructive in that it affirms one of Dr. Gregory House's pet assertions: "Everybody lies."

Interestingly, almost all of the recent confessions -- and there are hundreds of the things posted -- originate in towns bordering the one I lived in from the summer of 2004 to the spring of 2006 (Plantation, Florida, basically an exurb of Fort Lauderdale and Carl Hiaasen's hometown). In fact, I lived less than a mile from Flamingo Road. I can assure you that almost everyone around had plenty of things to atone for, especially the goddamned motorists.

May 4, 2008

Beta-catenin levels higher in alcoholics' brains, but does this make the protein a prevention or treatment target?

Category: The Medical Tent

Longest post title ever!

Researchers at Wake Forest have determined that the levels of a protein called beta-catenin are higher in the brains of longtime heavy drinkers than in age-matched controls free of alcoholism. Beta-catenin, like hundreds of other polypeptides, contributes to intracellular signaling and cell development. Of note is its apparent role in liver regeneration following partial hepatectomy or other insult.

Because ethanol is a poison that does not merely affect behavior and physiological processes but the structure of the body itself (cirrhosis, anyone?), I was already thinking along the lines of this observation from Qiang Gu, the study's senior author, before I got to it.

May 3, 2008

American track and field about to be walloped with the ugly stick: Trevor Graham on trial

Category: D'oh(pe)!

If there's one name that should have sent any sane sprinter barreling in the other direction in the past decade, it's Trevor Graham. Here is a guy who, in a septic and darkly impressive feat, has managed to be linked to virtually every doping scandal involving American track and field athletes since at least the 2000 Sydney Olympics. The North-Carolina based Graham was Marion Jones's coach toward the end of her career, and it was Graham who anonymously provided the U.S. Anti-Doping Agency with a syringe containing traces of "The Clear," a preparation containing the synthetic anabolic steroid THG, or tetrahydrogestrinone.

Graham, a member of the Jamaican 4 x 100m team that took silver at the 1988 Seoul Olympics, is scheduled to go on trial on May 19 for lying to the feds about his role in providing athletes with banned substances directly and referring those he did not supply himself to a Texas-based source. Although various high-profile athletes who have trained under or alongside Graham have already tested positive for or admitted to using illegal performance enhancers -- among them Jones, Tim Montgomery, Dennis Mitchell, Alvin Harrison, Justin Gatlin, C.J. Hunter, Jerome Young, Michelle Collins, and Bozo the Clown (okay, just checking) -- the list is about to get a lot longer.

May 2, 2008

Children, eating disorders, and fat: striking a balance in the classroom

Category: Health and Society

It wasn't so long ago that the only body-fluid derangement of consequence in the curious milieu of marathon running was dehydration. Even people who knew better were at risk; in the psychologically intense environment of a long endurance event, it is all too easy to pass up water or other fluids in favor of saying "I feel fine" and forging on. The results can be nasty indeed, even fatal.

Nowadays, the marathon world is rife with participant-entrants who are in it for the health benefits and the camaraderie rather than to compete -- folks whose aim is not to run fast but to simply finish. As a result, threats that were once rare to nonexistent have become comparatively common, because more and more people are out on the course for five, six, even seven hours, exposing them to problems that used to be seen only in triathlons or other ultra-endurance endeavors. One of these is hyponatremia, a condition in which serum sodium levels become so dilute as a result of drinking massive amounts of electrolyte-free water that fluid is osmotically "sucked" into the brain (where sodium levels remain normal), leading to progressive disorientation, stupor, and coma, sometimes with lethal consequence. This has spawned more than a few articles on the matter, and the result has been a "hydration backlash" of sorts, with runners warning one another of the dangers taking in too much fluid during a marathon.

However, as dangerous as hyponatremia can be, the fact remains that far more people continue to suffer from dehydration than from low sodium levels. Each extreme carries its own set of pernicious effects, but to highlight one is no excuse to ignore the other. People simply have to learn what to do to forestall both.

This has no topical bearing on what I'm about to write, but you'll soon understand why I brought it up.

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