Sodium borohydride (Medium reducing)
Category: Synthesis
Sodium borohydride is intermediate to the jackhammer that is LAH and the pussycat that is cyanoborohydride.
Posted by Molecule of the Day at 9:40 PM • 1 Comments
Molecules: You'd better learn to live with them.
August 19, 2008
Category: Synthesis
Sodium borohydride is intermediate to the jackhammer that is LAH and the pussycat that is cyanoborohydride.
Posted by Molecule of the Day at 9:40 PM • 1 Comments
August 13, 2008
Category: Poisons
Trying to think of a molecule tonight, my friend suggested "pick an ugly one no one wants anymore...a clearance rack molecule." I immediately went to chlorinated solvents. They're in the backwater now, right? Carbon tetrachloride sure has a bad rep. I figured most of the organochlorides, except for the ubiquitous lab solvents, would, too. I was wrong.
Posted by Molecule of the Day at 11:11 PM • 10 Comments
August 11, 2008
Category: Dyes
Pyrene is a simple, four-fused benzene PAH:
Posted by Molecule of the Day at 10:37 PM • 3 Comments
August 7, 2008
Category: Perfumey
I love reading lists of fragrance chemicals. The assignment of pleasant, qualitative fragrance descriptions to chemicals with hard-nosed, rigorous functional group names always makes me giggle a little. Acetophenone, for instance, smells of orange blossoms. Today, I came across one that has both in the name: dewy propionate:
Posted by Molecule of the Day at 8:26 PM • 2 Comments
August 5, 2008
Category: Not Really a Molecule
If you have been reading SB long enough to remember the DonorsChoose promotion, you might be interested in this. It's videos of scientists talking about their first experiments and why they like science, and if you vote on the one you like best, DC gets a buck. Check it out here.
Posted by Molecule of the Day at 9:00 AM • 0 Comments
August 4, 2008
Category: Food
Erythorbic acid is a common food additive:
Posted by Molecule of the Day at 8:01 PM • 1 Comments
July 29, 2008
Category: Drugs
As I mentioned yesterday, derivatives of arylethylamines - phenethylamine in particular - are drug targets in depression, but a sophisticated mechanistic understanding remains elusive. When you have some idea what molecule you'd like less of, a favorite trick is to find something (an "inhibitor") that binds to some enzyme in the pathway to your molecule and mucks up the works.
Posted by Molecule of the Day at 7:51 AM • 7 Comments
July 28, 2008
Category: Drugs
An aromatic ring, two carbons, and a nitrogen will get you a lot of places.From hallucinogens to decongestants to speed, the arylethylamine moiety works because it tickles neurotransmitter receptors. The effects of the assorted monoamine neurotransmitters are as varied as those of the drugs that mimic it - hypertensive, euphoriant, the works. This is part of how we try to explain to ourselves how antidepressants that block the breakdown of these neurotransmitters (MAO inhibitors) or their reuptake (SSRIs) might be working. What might happen if you took something that depleted some of those monoamine neurotransmitters?
Posted by Molecule of the Day at 1:14 AM • 2 Comments
July 24, 2008
Choline is an ubiquitous vitamin. Interestingly, it makes a number of "deep-melting eutectics" with other dirt-common chemicals like Urea.
Posted by Molecule of the Day at 11:58 PM • 2 Comments

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