Methyltriphenoxy phosphonium iodide (Iodine time)

By moleculeoftheday on August 22, 2007.

This reagent is one of my favorite ones for replacing an alcohol with an iodine.

i-40bad92267b21125b10a2354e60d0dac-methyltriphenoxyphosphoniumiodide.gif

Eric Kool's lab has made good use of it to iodinate the 5'-OH after automated synthesis of a DNA strand.

More like this

Advertisment

Donate

ScienceBlogs is where scientists communicate directly with the public. We are part of Science 2.0, a science education nonprofit operating under Section 501(c)(3) of the Internal Revenue Code. Please make a tax-deductible donation if you value independent science communication, collaboration, participation, and open access.

You can also shop using Amazon Smile and though you pay nothing more we get a tiny something.

Science 2.0

Science Codex

More by this author

VX (Kills bugs and people dead)

January 27, 2011

A US Army base in Utah was locked down for some time on Wednesday, because they discovered that they (transiently) misplaced a container of VX - a potent chemical weapon. Like they used in The Rock! A neurotransmitter called acetylcholine (or ACh) helps your muscles contract, as well as regulating…

Brominated Vegetable Oil (Making orange soda look more like OJ)

May 7, 2010

When you mix bromine with another molecule that has a carbon-carbon double bond, the bromine can add across the double bond. The bromine atoms are very heavy - about 80 times as heavy as a hydrogen atom, or 7 times as heavy as a carbon atom. Bromination usually gives you a molecule that has higher…

Dapoxetine (No, it's supposed to do that!)

April 29, 2010

If you take or are close to someone who takes antidepressant medication, you're probably aware that one class, the SSRIs, is particularly prone to causing sexual side effects. These effects can run the gamut from inhibition of libido, to erectile dysfunction, to a diminished or complete inability…

Slentrol/Dirloapide (Got a fat dog?)

June 4, 2009

Wow. It's not just anticancer drugs for dogs, there are also "lifestyle" drugs. They think they're people! Just like people obesity drugs, they're intended for short-term use, coupled with a diet and exercise plan. I really don't understand. It's not hard to put your dog on a diet. See here if you…

Palladia/Toceranib (Dog cancer drugs)

June 3, 2009

A few months ago, a tyrosine kinase inhibitor anticancer drug for people, this month, one for dogs. It is made to treat cutaneous mast cell tumors, which apparently account for about a quarter of dog cancers. I know a lot of people drugs end up in pets, but do pet drugs ever end up crossing over…