LSD

The U.S. "war on drugs," besides failing to meet its goals, has demonstrated a stubborn ignorance of the effects that different drugs have in the human body. Granted, some drugs cause degeneration and are properly outlawed. Opiates such as heroin and stimulants such as cocaine and methamphetamine take a harsh physical toll and leave users addicted to the chemical. But classified along with these truly dangerous drugs are some of nature's most mysterious medicines. New research shows how marijuana, psychedelics, MDMA and even ketamine have positive physiological and psychological effects that…
"If I see a spider in my house, I put it in a cup, and then I take it outside. I save it. What is wrong with me?" -Jacqueline Emerson There's something not only incredibly useful but also beautiful about the intricate structure of a spider web. It's such a universally admired phenomenon that it's become a metaphor for many other things, as Welbilt sings you in their song, Spiderweb. Dependent on the type of spider and various environmental factors, the web can take on any number of beautiful shapes. Image credit: Darlyne Murawski, via National Geographic Society, 2007. Image credit:…
“Life should not be a journey to the grave with the intention of arriving safely in a pretty and well preserved body, but rather to skid in broadside in a cloud of smoke, thoroughly used up, totally worn out, and loudly proclaiming, 'Wow! What a Ride!'” -Hunter S. Thompson For those of you who've never experienced exactly what it feels like to alter your perceptions, and for those of you who have but don't want to spend hours and hours experiencing the effects, your options have traditionally been limited. Perhaps a song might provide a window into the experience for you, such as M. Ward's…
This post is part of a Nature Blog Focus on hallucinogenic drugs in medicine and mental health, inspired by a recent Nature Reviews Neuroscience paper, The neurobiology of psychedelic drugs: implications for the treatment of mood disorders, by Franz Vollenweider & Michael Kometer. This article will be freely available, with registration, until September 23.  See the Table of Contents for more information on this Blog Focus, and read the other blog posts: Serotonin, Psychedelics and Depression (by Neuroskeptic) Ketamine for Depression: Yay or Neigh? (by The Neurocritic) Visions of a…
Welcome 4 March readers of The Daily Grail - please be sure to also click on the original post about the DMT article by my colleague, Laura Mariani. Thanks to Dave Munger & Co's ResearchBlogging.org, I just found a fabulous neuroscience grad student blogger from Emory University: Laura E Mariani at Neurotypical? Doctor-to-be Mariani blogged last Monday about a paper in Science where the endogenous ligand of the orphan sigma-1 receptor was identified as the hallucinogen, N,N'-dimethyltryptamine, or DMT. The work originated with the group of Arnold Ruoho and colleagues at the University…