schizophrenia

...for rodents and men at least. A team of researchers at UC Berkeley have discovered that mice infected with the parasite Toxoplasma gondii lose their innate fear of cats, even months after the infection is cleared. In fact, infected mice were mildly attracted to the odor of cats. This side effect likely evolved because the parasite can only sexually reproduce in a cat's gut necessitating ingestion of the parasite. Incidentally, other researchers have described the same side effects in rats and men (but not women). The findings suggest that the parasitic infection causes permanent changes in…
Take a bunch of peculiar individuals, put them all together in one setting; film their every move, every second of the day. Sound familiar? Dr. Tali Kimchi is explicit about the resemblance of her experiments to a well-known reality TV show. The difference, of course, is that Kimchi’s subjects are mice. She places large groups of animals in a common pen in her lab, which is fitted out with video cameras, infrared lighting for nighttime filming and electronics to continuously record information from the ID chips implanted in each mouse. And while no one can deny that our enjoyment at seeing…
Student guest post by Zainab Khan Schizophrenia has puzzled and often times scared not only the scientific community, but also the general public since its emergence. Cases of schizophrenia-like behavior have been well documented in history. As this disease has been studied, factors such as genetics, environment, and even personal habits have all been associated to some degree with schizophrenia. However, evidence in past years has mounted showing an association between infectious agents and schizophrenia. The three main infections associated/studied with schizophrenia have been…
tags: religion, violence, mental illness, fundamentalism, MtlRedAtheist, streaming video This is the first in a series of videos that address some of the violent, absurd and atrocious Bible stories being taught to children in Sunday School around the world today. This video discusses how Abraham almost murdered his son because he heard god telling him to do so. And people wonder why fundamentalists of all Abrahamic religions are so violent? This story is about Abraham and Isaac. In the Bible, God wanted to test Abraham's faith by commanding him to murder his son as a sacrifice. Abraham was…
Below I repeated the contention that while schizophrenia is a genuine biologically rooted behavioral disease which can not be cured through will, many forms of addiction are not. That is why the genetics of schizophrenia are of such great interest, if the biological pathways of the pathology can be elucidated presumably a cure may be found. Unfortunately finding the genes is easier said than done, see Schizophrenia: The Mystery of the Missing Genes.
Purcell et al. (2009). Common polygenic variation contributes to risk of schizophrenia and bipolar disorder Nature DOI: 10.1038/nature08185 Neil Walker has been doing a spectacular job of serving up useful information in the comments recently, so I asked him to write the first ever guest post on Genetic Future - something that (as I will be announcing shortly) I intend to do fairly regularly over the next couple of months. The topic is a paper that has created a rather perplexed buzz recently in the complex disease genetics community: the genome-wide association study (GWAS) for…
I must keep my nose on the not-beta, hidden-till-last-minute, writing-Not-For-FREE grindstone, where it's getting shredded to bits -- but in the meantime, wanted to pass on these worthy web distractions, worthy of full engagement if you've the time: Vaughan Bell peeks at The long dark nightie of the soul and wonders "why mentally distressed women are always portrayed in their nighties." Separately, he considers some strange security concerns raised by the growing use of brain implants. Much interesting attention to schizophrenia this week: A big study parsing the genetics of schizophrenia,…
The Onion News Network brings us In The Know: Is The Government Spying On Paranoid Schizophrenics Enough? Satire of a talk show with pundits who promote more and better spying on people diagnosed with paranoid schizophrenia. Note: It's "people diagnosed with" (or just "people with") and not "schizophrenics" as people are more than their differences and labels. But that's not as funny, is it?
tags: suicide, world suicide prevention day, mental health, depression, bipolar disorder Suicide is a major public health issue and accounts for nearly 3% of all deaths worldwide -- around the world, one million people will die by suicide this year. But suicide is a taboo subject that many people, regardless of age, sex, socioeconomic status or religious and cultural affiliations, are ashamed of, and rarely speak about. This veil of secrecy leads to needless deaths worldwide. So as a result, today was designated as World Suicide Prevention Day, which is designed to raise public awareness of…
OK, so I am not actually on this paper, but my boss is. It is also what I am doing my thesis on, so I thought I might mention it. The article is entitled "Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia" and was published in the August 4th issue of PNAS. For many years all the work on schizophrenia focused on the dopamine system -- I think this is largely because dopamine-affecting drugs are used to treat it. There was also a great deal of interest in other transmitters such as glutamate, in part…