Bioethics

Gardasil is the vaccine from Merck that greatly lowers the risk of infection from some human papilloma virus (HPV) infections. The href="http://scienceblogs.com/ethicsandscience/2006/06/hpv_vaccine_approved_daughters.php">first big controversy had to do with the practice of giving the vaccine to young girls.  To be most effective, it should be given prior to the commencement of sexual exposure.  So the recommendation is to give it to girls at age 12.  This led some persons to complain that it might encourage sexual activity in contexts they deemed inappropriate. The ethics of this have…
She was thin, white skin stretched over bones like worn parchment over old sticks being rhythmically blown in the wind as her chest rose and fell, each time with what seemed like a major effort. Incongruous with the rest of her body, her abdomen was distended, a balloon that looked dangerously close to popping, also rising and falling with each breath. She moaned softly and looked at me. I introduced myself, told her I was a surgeon, and continued, "Your oncologist asked me to see you about your belly pain." "Go ahead," she croaked, hardly acknowledging my presence in the way that patients…
After having subjected my readers to all those posts about the antivaccination lunacy that was on display in Washington, D.C. last week, I think it's time for a break from this topic, at least for a while if not longer. In the run-up to the "Green Our Vaccines" rally events on the antivaccinationism front were coming fast and furious, and I felt it was my duty to comment on them. Now, with great relief I can say that the rally is over. How many people actually attended the rally is uncertain. The organizers themselves claim that 8,500 people attended, while more objective estimates from…
Believe it or not, even I, Orac, sometimes get tired of blogging about antivaccination idiocy. Indeed, this week was just such a time. I hope you can't blame me. After all, the last few months have been so chock-full of some of the most bizarre and annoying antics of antivaccinationists at such a frequent clip that there was just no way I could even keep up with it, and trying was starting to burn me out. (I guess there's only so much that the stupid can burn before even Orac's nearly indestructible clear plastic case can handle before he needs a break.) Truth be told, not wanting Respectful…
Regular readers here are probably most familiar with the so-called "complementary and alternative medicine" therapy known as chelation therapy in the context of its use, or, more specifically, its misuse in "treating" autistic children, a misuse that has resulted in at least one death, a five-year-old autistic boy named Abubakar Tariq Nadama. However, before the profit potential of chelating nonexistent mercury in autistic children was even a gleam in Dr. Roy Kerry's eye, there was another equally dubious use of chelation therapy: to treat atherosclerotic coronary artery and peripheral…
OK, I know it's like the post calling the kettle black, but what the heck is PalMD doing blogging on vacation? And are his two most recent posts so good? This is what I mean: Why hospice matters Never say "hopeless" I recently had the unfortunate opportunity to visit a relative in hospice. I was incredibly impressed. Nice, well-appointed rooms, with a caring, attentive staff that did everything in its power to keep the dying as comfortable and free of distress, both physical and emotional, as humans can do. As a cancer surgeon, I've been involved with a number of patients who went to hospice…
Dr Kimball Atwood IV at Science-Based Medicine and my long-time blogging colleague Orac have spilled oceans of e-ink on the institutionalization of alternative or integrative medicine in North America's top academic medical centers. Complementary and alternative medicine (CAM) is now often called "integrative medicine" to intellectually justify the incorporation of evidence-free, anecdotal practices into the business of academic medicine. Of course, integrative medicine does co-opt a few areas of conventional medicine, like nutritional and psychological counseling, supported by an evidence…
I'm not normally one to do link roundups or Instapundit-style one sentence "link and comment" posts. Sure, I do them occasionally, but I think the reason that I don't is that to me blogging is a way to express my views, not just to point to the views at others (in other words, because I'm just too enamored of my own prose). However, because of a bizarre confluence of my being at the AACR meeting and a bunch of good stuff showing up, there were some items that I just didn't have the chance to comment on, even though I wanted to. Moreover, because I want to do a couple of posts on the AACR…
Here at ScienceBlogs, we've regularly posted about the thorny issue of antibiotic overuse, and the subsequent antibiotic resistance.  This is a good example of evolution in action; it's also a good reason why we need to study and understand evolution.   But antibiotic resistance is not the only such example.  The same principle applies to herbicides and weeds. Naturally, a good example comes to us courtesy of href="http://www.monsanto.com/" rel="tag">Monsanto, the company that href="http://www.vanityfair.com/politics/features/2008/05/monsanto200805?printable=true&currentPage=all"…
Nasal drone Ben Stein, as you would be hard-pressed not to know if you are a regular reader of ScienceBlogs, is hosting what looks to be a truly execrable crap-fest called Expelled!: No Intelligence Allowed. The movie basically consists of two themes: (1) Whining about "intellectual oppression" by those evil "Darwinists" directed against any valiant "intelligent design" creationist or anyone else who "questions" Darwin and (2) lots of blaming the Holocaust and other atrocities (but mainly Hitler and the Holocaust) on "Darwinism," replete with lots of shots of Nazis, Ben Stein clumsily emoting…
The death of a euthanasia-advocate, who suffered from a debilitating cancer that ate away at her face, has re-kindled the debate over doctor-assisted suicide in France. A French law adopted in 2005 allows terminally ill people to refuse treatment in favor of death but stops short of allowing active euthanasia, says this CNN article. Interestingly, active euthanasia is legal in some neighboring countries like Netherlands, Belgium, Luxembourg and Switzerland. Read more here.
There's no doubt about it: Stem cells are hot. Yes indeed, they're not only hot, but they're hip, they're happenin', they're right now, baby. Scientists are falling all over themselves with excitement at the potential applications that could potentially come from stem cell technology. True, no validated therapies for embryonic stem cells have yet made it into clinical practice, and the challenges that need to be overcome before that can happen are arguably greater than what was believed in the heady days a few years ago, before President Bush declared his ill-advised restriction on embryonic…
One of the greatest threats to the preclinical research necessary for science-based medicine today is animal rights activism. The magnitude of the problem came to the forefront again last month with the news that animal rights terrorists tried to enter the home of a researcher at the University of California Santa Cruz (UCSC) whose research uses mice to study breast cancer and neurologic disease while she and her husband were having a birthday party for one of their children and assaulted her husband, who had gone to the front of the house to confront them. This unrelenting attack on the use…
Perusing the news early this morning, I noticed an article on ABC News about placebos. One thing I found interesting about it was that it was a story about a research letter to JAMA, not a full study. Heck, there isn't even an abstract. Even so, the study was rather interesting and described thusly: The more expensive your pain medications are, the better the relief you get from taking them -- even if they're fake. That's according to a study published this week in the Journal of the American Medical Association, which suggests that sugar pills labeled as expensive drugs relieve pain better…
[Note: I originally posted this last Thursday under another title but it got lost in other events of that day. As I find it ironic that Mr Comarow has been attacked by an alternative medicine practitioner and advocate, I find this story worthy of reposting.] A few weeks ago the skeptical blogosphere was up in arms about an article in US News & World Report by Avery Comarow on alternative medicine services in US academic medical centers. Mr Comarow is a senior medical writer for USN&WR and best known as editor for the last 18 years of the magazine's annual feature, America's Best…
A fellow blogger, Logtar,  href="http://blog.logtar.com/2008/02/18/bodies-revealed-boycott/">tipped me off to a controversy, and asked if I had anything to say about it.  The controversy has come about over an exhibit: rel="tag" href="http://www.bodiesrevealed.com/index-home.html">Bodies Revealed.  It's a traveling exhibit that displays plastinated human cadavers.  The exhibit was organized by href="http://www.prxi.com/prxi.html">Premier Exhibitions, Inc. A bit of background can be gotten from an article in Scientific American, href="http://www.sciam.com/article.cfm?id=…
Earlier this month, I was remiss in not noting an update to a story about which I had written before, a story of domestic terrorism carried out by so-called "animal rights" advocates who are utterly opposed to the use of animals in research. The series of attacks began with an intimidation campaign against a UCLA researcher named Dario Ringach that succeeded in frightening him to the point where he gave up doing primate research. Against Ringach himself, the campaign consisted primarily of harassment by phone and other means. However, Ringach was spooked by a botched attack on another UCLA…
For more details on this story, you can go to Mark Chu-Carroll, Orac, Mike the Mad Biologist, or the Autism Blog. I just wanted to share my personal views on the need for childhood vaccinations and support a public information campaign from the AAP. Until I started medical blogging, I had not realized quite how vocal was the community of individuals refusing to vaccinate their children, mostly at the urging of those who claimed that vaccines and related components caused illness in their own children. I will first say that no drug product, natural or otherwise, is completely and absolutely…
David Colquhoun, eminent scientist and maintainer of the excellent blog DC's Improbable Science, has recently returned home to the U.K. after a trip across the pond to the U.S. and Canada, where, among other things, he gave a lecture at the University of Toronto, as well as the Riker Memorial Lecture at the Oregon Health and Science University. Now that he's back, he's made some observations about the infiltration of quackademic medicine into U.S. medical schools, the same infiltration of woo that I've lamented in my Academic Woo Aggregator. Among his commentary on several "luminaries" of the…
Three weeks ago, I wrote about some truly irresponsible antivaccination propaganda masquerading as entertainment that aired in the form of a television show called Eli Stone. This show, which portrayed its hero taking on the case of an autistic boy whose mother blamed his autism on thimerosal (going under the fictional name "mercuritol") in vaccines and scoring a $5.2 million settlement in the process. One consequence of this show was that the American Academy of Pediatrics (AAP) was shaken out of its inaction enough to draft a letter protesting the show and urging its cancellation of the…