chemotherapy

I've spent a lot of time on this blog discussing failures of the medical system. Usually, such discussions occur in the context of how unscientific practices and even outright quackery have managed to infiltrate what should be science=based medicine (SBM) in the form of so-called "complementary and alternative medicine" (CAM) or "integrative medicine," in which the quackery of alternative medicine is "integrated" with SBM. However, as big a problem as the infiltration of unscientific CAM practices into medicine is, there is a threat at least as grave here in the U.S. (and, I presume, in many…
Eric Merola alternates between offending me and making me laugh at his antics. Since it's been a couple weeks since I've written anything about the Houston doctor who claims to be able to do so much better against many forms of cancer than conventional medicine, I have to express a bit of gratitude to Mr. Merola for giving me today's topic for blogging. Mr. Merola, as you recall, produced two incredibly bad and deceptive movies lionizing that very same Houston cancer doctor as a brave maverick genius who's been kept down by The Man (i.e., the Texas Medical Board, the FDA, the National Cancer…
Well, I've finally seen it, and it was even worse than I had feared. One might even say that watching it was like repeatedly smacking my head into a brick wall. It felt so good when it finally stopped. I'm referring, of course, to Eric Merola's latest cinematic "effort. Ever since it was revealed that ric Merola's planned to make a sequel to his 2010 propaganda "documentary" about Stanislaw Burzynski, Burzynski The Movie: Cancer Is Serious Business, whose rank stupidity provided me with copious blogging material, I've finally actually seen the finished product, such as it is. Of course,…
A key pillar of the Stanislaw Burzynski antineoplaston marketing machine, a component of the marketing strategy without which his clinic would not be able to attract nearly as many desperate cancer patients to Houston for either his antineoplaston therapy (now under a temporary shutdown by the FDA that, if science were to reign, will become permanent) or his "personalized gene-targeted cancer therapy," which Burzynski represents as a discovery of his that large NCI-designated comprehensive cancer centers like M.D. Anderson or Memorial Sloan-Kettering are only now starting to copy, is the…
New research at the Institute may offer a sliver of hope for treating “triple-negative” breast cancer. “Triple-negative” refers to the fact that the breast cancer cells are missing the three different receptors targeted by the currently available drugs, for instance Herceptin and steroid hormone blockers. This type of cancer also tends to be fairly aggressive, and the risk of early recurrence is higher than for other types of breast cancer. Triple-negative breast cancer cells do have other receptors – particularly EGFR, a growth factor receptor that would seem to be a good target for…
It's known as "targeted" therapy, and it's the holy grail of cancer research these days. If you listen to its most vocal proponents, it's the path towards "personalized medicine" that improves survival with much lower toxicity, in which, instead of using the hammer that is chemotherapy, precisely targets specific molecular abnormalities that drive cancer growth. With the advent of the revolution in genomics that has transformed cancer research over the last decade, including the petabytes of sequence and gene expression data that pour out of universities and research institutes, the promise…
Washington State becomes the first in the nation to adopt specific workplace safety rules to protect healthcare workers who are potentially exposed to anti-neoplastic drugs and other hazardous medications. The new rule, issued earlier this month by the State's Department of Labor & Industries, stems from legislation passed in April 2011 and signed into law by Governor Chris Gregoire. The rule applies to healthcare facilities in which employees are "reasonably anticipated" to have "occupational exposure to one or more hazardous drugs." The CDC's National Institute for Occupational…
What is it with cranks and trying to shut down criticism? I know, I know. I've written about this before, but this week has been a banner week for a phenomenon that I consider a sine qua non of a crank or a quack, namely an intolerance of criticism. Seemingly, whenever a quack or a crank encounters serious criticism, the first reaction is almost never to try to argue based on facts, reason, and science, but rather to try to silence the person doing the criticizing. The tactics are many and varied, but the end goal is always the same: Suppress the criticism by any means necessary. The very…
USA Today reports the curious case of a Singapore man who was detained for several hours by airport security when they couldn't find his fingerprints. The man, who was taking capecitabine as part of chemotherapy treatment, suffered from hand-foot syndrome, a side effect of the drug where skin peels off. His oncologist describes the unusual case today in an online letter to the Annals of Oncology. The problem is not as rare as you might think. Around one in 50 people in the world lack identifiable fingerprints; an official from the Department of Homeland Security reported "We have standard…
Yesterday, I wrote about Daniel Hauser, a 13-year-old boy with Hodgkin's lymphoma who, with the support of his parents, has refused conventional therapy for his cancer, which would normally consist of chemotherapy and radiation. Given his stage and type of tumor, he could normally expect at least an 85% chance of surviving and perhaps even greater than 90%, wherea without therapy he is certain to die of his disease, barring a rare spontaneous remission. The reason given by his Daniel and his mother Colleen is that they belong to a highly dubious-sounding American Indian religion called…
PZ's muscling in on my territory. Apparently, ruling the Darwinian, creationist-destroying atheist cephalopod blogging world isn't enough, and he has to start moving in on medicine. No problem, given that this time around he brought some rather interesting woo to my attention, suggesting it as perhaps a suitable topic for Your Friday Dose of Woo called God's Answer to Cancer. Besides, it's PZ's birthday; so as a birthday present, instead of reposting the same silly picture that I have for the last two years, I'll simply link to him now and add, oh, perhaps 1% to his traffic total for today…