drugs of abuse

Yesterday, we received tomorrow's issue of the New England Journal of Medicine and, yet again, I nearly walked into a tree coming back from the mailbox. This (abstract, full text), folks, is a fascinating medical detective story rivaled only by (and similar to) the discovery that Parkinson's disease could be caused by contaminant from a faulty clandestine synthesis of an analog of the opiate, meperidine. (1979, 1983) Here's the backstory: in the US, our newly-implemented restrictions on ephedrine and pseudoephedrine OTC drug products are due to the use of these chemicals as starting…
DrugMonkey just had an interesting post about the potential influence of cocaine use trends following the 1986 death of Maryland college basketball player, Len Bias, just days after his being selected in the NBA draft by the Boston Celtics. DM's post and the ensuing discussion got me thinking tonight about a variety of issues in substance abuse, realistic assessment of risk and, ultimately, parenting. In the comments, I mentioned that Heath Ledger's recent death might be a trigger for pop culture to pay more attention to the risks of recreational use of prescription and over-the-counter…
tags: mouse party, drugs, drug mechanisms, illegal drugs, video game, educational tool Now that the school year has started again, I think it is worthwhile to repeat an earlier blog entry where I linked to a really interesting interactive game, called Mouse Party. This interactive game is a great educational tool, teaching you how various legal and illegal drugs work in the brain. Have you ever wondered how various drugs work in the brain to produce the symptoms they do? Well, this wonderful interactive website, Mouse Party, shows you the molecular details of how heroin, exstacy, alcohol,…