influenza
tsmith | January 10, 2006Okay, one more quick post. I've talked quite a bit on here (and over on Panda's Thumb) about the importance of surveillance, and how the current death rates from H5N1 influenza ("bird flu") are likely to be artificially high, since we're more likely to diagnose the very ill cases than the mild or asymptomatic ones. (See here and here for the relevant posts). Indeed, that first post linked discusses a study carried out here at the Center for Emerging Infectious Diseases at the U of Iowa, which found that swine workers were much more likely to be infected with swine influenza viruses than those…
tsmith | November 22, 2005I've mentioned many times on here reservations I have over the current avian flu numbers--how many subclinical or mild infections are being missed? Are they indeed offset by the number of serious disease cases we're also missing? There's a reason for these questions, and it's now out in electronic form in Clinical Infectious Diseases.
A bit of background. I work in Iowa as part of the Center for Emerging Infectious Diseases. One of our pet pathogens happens to be influenza virus, and we have ongoing studies looking at serological evidence of prior infection with swine and avian viruses in…
tsmith | October 18, 2005Ah, how rare is it that my interest in stomping creationists and my interest in infectious disease collide. But I guess that when there's a topic as hot as avian influenza, it's inevitable that even the folks at the DI will sit up and take notice, as Casey Luskin has in this post: Avian Flu: An Example of Evolution?
First, as Luskin admits in the article, the answer to his titular questions is, "well, duh; of course it is." And alas, it doesn't get any better from there.
Allow me a moment to rant a bit here. It's painful for any expert in a field to read articles authored by those who are…
tsmith | October 7, 2005Thus far this week, I've discussed the history of pandemic influenza in general, and avian flu in particular. I've discussed some issues that must be addressed to prepare us for a pandemic, and the groundbreaking resurrection of the Spanish influenza virus. Today I want to end the series with a look at how prepared we currently are as a nation, and highlight some personal preparedness steps you can take.
If you recall from Tuesday, the first outbreak of H5N1 was back in 1997. The anthrax attacks were in 2001. Surely by now we're prepared for some kind of serious, large-scale, biological…
tsmith | October 6, 2005I know I said I was going to discuss a bit more about pandemic preparedness today, but I think I'll hold off on that to discuss this story:
It sounds like a sci-fi thriller. For the first time, scientists have made from scratch the Spanish flu virus that killed millions of people in 1918.
Why? To help them understand how to better fend off a future global epidemic from the bird flu spreading in Southeast Asia.
Researchers believe their work offers proof the 1918 flu originated in birds, and provides insights into how it attacked and multiplied in humans. On top of that, this marks the first…
tsmith | October 5, 2005The scientific community is all too familiar with the dangers an influenza pandemic could bring. The politicians and general public are starting to become aware of the issue as well; indeed, one can hardly open a newspaper or turn on the television without hearing about "bird flu." So, what's actually being done to prevent an influenza catastrophe? What are the issues? What can be done?
These are the questions that keep public health officials awake at night, because the answer is always that we're not doing enough. While we may be resigned to the fact that a future pandemic can't be…
tsmith | October 4, 2005Anyone working in the area of influenza virus epidemiology is familiar with the name Robert Webster. A virologist at St. Jude's Children's Hospital in Memphis, the native New Zealander has been leading the charge against influenza for well over 40 years. Barely out of graduate school, Webster hypothesized that something like genetic reassortment (which had not yet been discovered) occurred to cause the big changes that appeared among human influenza viruses, driving pandemics. He performed a simple experiment that cemented the course of his career: he found that serum from patients who had…
tsmith | October 3, 2005It's hard to avoid hearing about influenza virus these days. In all the noise, it's tough to sort out the facts from the rumors and conspiracy theories. I've already discussed a bit about the basic biology of the virus in this post, so I'm not going to review that here (though a good overview can be found here for those of you who need to bone up on your influenza virus biology). So, this week, as a part of Pandemic influenza awareness week, I'll be writing a 5-part series about various issues regarding influenza. Today, I'll discuss the history of influenza, focusing on past pandemics. The…
tsmith | September 26, 2005Canine flu strikes in Westchester county, NY.
A NEW strain of influenza that began infecting dogs in Florida early last year has recently struck hard in the Westchester area, forcing the temporary closure of two kennels after more than 100 dogs being boarded there became ill, veterinary officials say.
Gracelane Kennels in Ossining underwent decontamination after a viral illness infected dogs. Eddie Loga hoses down a run at the kennel. Although prepared for the less-virulent kennel cough, boarding sites have been blindsided by the new virus.
At least one of the dogs has since died. The two…