Molecular Evolution

Are There Disagreements Between the Fossil Record and Molecular Data? Molecular biologists have a tradition of reworking a lot of the evolutionary relationships and timescales that morphologists and paleontologists worked so hard to figure out. This can really piss off the non-molecular folks, but I prefer to think of it as a cooperative relationship. The molecular clock, for example, would not be possible without calibration from the fossil record. It is important to note that molecular and morphological data tell two different stories, which I outline below the fold . . . When I wrote…
PZ Myers is reposting some of his greatest hits from the old Pharyngula website to his new digs at ScienceBlogs. In one post he gets into the deficiencies of modern evolutionary theory using West-Eberhard's book as a guide. I agree with most of the thing he says (and I'll get into how I agree with him below), but first I need to scratch a pet-peeve itch: "You can see this in any textbook of population genetics: the effect of selection is to impose a gradual shift in the mode of a pattern of continuous variation. Stabilizing selection chops off both tails of the distribution, directional…
I have been describing some recently published worked on polymorphic deletions (see here and here for the previous two posts) on the old site. I will conclude that series here at ScienceBlogs with a discussion of linkage disequilibrium and deletions. In the previous two posts I outlined two different approaches for identifying polymorphic deletions using single nucleotide polymorphisms (SNPs). I also described some of the analysis performed on that data set, which revealed that many of the deletions resulted in the elimination of at least a portion of a gene (some removed complete genes,…