Just came back from Montreal. We attended a wedding, a thanksgiving feast, and countless outings. Basically lots of eating and drinking. I just read at ScienceSampler that interfering with actin polymerization enhances ethanol tolerance. If only I knew. The only question left is that will it cure your hangover?
(Actually it shouldn't as hangovers are produced mainly from sulfide consumption + dehydration.)
Ref:
Increased Ethanol Resistance and Consumption in Eps8 Knockout Mice Correlates with Altered Actin Dynamics
Nina Offenhäuser, Daniela Castelletti, Lisa Mapelli, Blanche Ekalle Soppo, Maria Cristina Regondi, Paola Rossi, Egidio D'Angelo, Carolina Frassoni, Alida Amadeo, Arianna Tocchetti, Benedetta Pozzi, Andrea Disanza, Douglas Guarnieri, Christer Betsholtz, Giorgio Scita, Ulrike Heberlein, and Pier Paolo Di Fiore
Cell, Vol 127, 213-226, 06 October 2006
Distinct Behavioral Responses to Ethanol Are Regulated by Alternate RhoGAP18B Isoforms
Adrian Rothenfluh, Robert J. Threlkeld, Roland J. Bainton, Linus T.-Y. Tsai, Amy W. Lasek, and Ulrike Heberlein
Cell, Vol 127, 199-211, 06 October 2006
