Dan MacArthur's post, Can't find your disease gene? Just sequence them all..., is worth a read. He concludes:
But sequencing won't be enough: we need much better methods for sifting out the truly function-altering genetic variants from the biological noise. This is already difficult enough for protein-coding regions (as this study demonstrates); we currently have virtually no way of picking out disease-causing variants in the remaining 98% of the genome. There's a clear need for developing highly accurate and comprehensive maps of the functional importance of each and every base in the human genome, using all of the tools at our disposal - something that will keep us geneticists busy long after we've run out of genomes to sequence.
More like this
The world of genomics is changing. It was initially about sequencing the genome a single representative individual from a particular species.
...that is, if you still think that a genome sequence tells all secrets about someone's success in science etc. ;-)
What happens when I mention a paper describing two more Drosophila genomes?
Genome size can be measured in a variety of ways. Classically, the haploid content of a genome was measured in picograms and represented as the C-value.