Revealed: watch an infection develop in real time 3D

The BBC reports that for the first time, scientists have been able to watch the an infection develop in real time, inside an animal. The best part? They used a special glowing bacteria and measured the rays of light escaping from the animal's body:

The researchers used a genetically modified version of a mouse bug, Citrobacter rodentium, which produces light.

Dr James Collins, who works in Prof Frankel's lab, then puts the infected mice inside the scanner.

"It is a dark box which keeps the animals warm and blocks any other light from coming in. It has a camera at the top so we can very sensitively measure any light that's emitted through the mouse by the bacteria."

He then uses the measurements to build up a map of the exact location of the bacteria in different parts of the body. The amount of light escaping shows how many bacteria there are. More light means more bacteria and if the light starts to go out then that means the bacteria are being killed off.

Repeating these scans, with the same mouse, day after day, builds a complete picture of an infection.

The equipment can also be configured to look in exquisite detail at the immune system. Dr Collins said: "We can image where the bacteria are and where and which types of immune cells have been recruited to that area."

Link: Watching an infection take hold in 3D and in real time, BBC


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Jeez, more lab genetic pretend life modelling, are my taxes paying for this crap.

By buckthetrend (not verified) on 03 Jul 2012 #permalink

No, Buck, this is actual,meat-space modelng, and a thrilling development that may have far-reaching effects to benefit human health. Too bad you won't be able to use it. Maybe you could enroll in the chimp studies?

By Butch Pansy (not verified) on 03 Jul 2012 #permalink

derp derp, dem scientists usin all my money for these stupid ge-net-ic tests 'n all that garbage. The good ol' medicine whiskey has always worked for my mom and pop and their mom and pops. Stupid scientists think they know everything.

By buckbuckthetrend (not verified) on 03 Jul 2012 #permalink