enthalpy

Paper Up: Correlations between DNA binding thermodynamics and DNA polymerase activity

vlicata | September 14, 2013

Our lab has a paper called: "Enthalpic Switch-Points and Temperature Dependencies of DNA binding and Nucleotide Incorporation by Pol I DNA Polymerases" that was just published in BBA (Biochimica et Biophysica Acta): Proteins and Proteomics. The study follows up on an observation and prediction we had made some years ago in a different paper. The study deals with quite a lot of rather detailed thermodynamics of DNA binding (free energy, enthalpy, entropy, heat capacity…) and looks for correlations between such thermodynamic measurements of binding and the functional behavior of a couple of…

Advertisment

Donate

ScienceBlogs is where scientists communicate directly with the public. We are part of Science 2.0, a science education nonprofit operating under Section 501(c)(3) of the Internal Revenue Code. Please make a tax-deductible donation if you value independent science communication, collaboration, participation, and open access.

You can also shop using Amazon Smile and though you pay nothing more we get a tiny something.

Science 2.0

Science Codex

Paper Up: Correlations between DNA binding thermodynamics and DNA polymerase activity

Ask Emmy Questions

The Lights Stay On Inside a Black Hole!

Tet Zoo 5th birthday extravaganza, part II