genetic structure
razib | May 15, 2009Genome-wide Insights into the Patterns and Determinants of Fine-Scale Population Structure in Humans:
Studying genomic patterns of human population structure provides important insights into human evolutionary history and the relationship among populations, and it has significant practical implications for disease-gene mapping. Here we describe a principal component (PC)-based approach to studying intracontinental population structure in humans, identify the underlying markers mediating the observed patterns of fine-scale population structure, and infer the predominating evolutionary forces…