The mRNA Song

Well I am trying to decide whether to attend this year's RNA Society Conference. As I'm a neophyte to the field (my PhD thesis was on microtubules in migrating cells), I learned quite a bit at last year's meeting. But it's going to be a hectic spring and summer for me. What to do?

As I'm flipping through the RNA Society newsletter, what do I see ... the mRNA song. Apparently this first appeared in Scott Gilbert's Developmental Biology.

The mRNA Song
Tune: YMCA

Student! I was once in your shoes;
Got no staining
On my Coomassie Blues,
All my training
Was just paying my dues;
I could not get good data,

Then, someone
Said: Persulfate wonât do
And the Lowryâs
Should be flushed down the loo.
They smell flowery,
But they will not get you.
Any answers;
So study the

M-R-N-A
(yes, we study the)
M-R-N-A
It comes straight from the gene,
It can make a protein,
Itâs the code that connects
The whole cellular machine!

Then I
Got the data galore,
Got new answers,
With each gel that I pour;
With enhancers,
I can even get more.
And I churn
Out the papers.

So student,
If your work has been slowed,
Skip the protein
And go straight for the code.
Do in situs
On a fly, mouse, or toad.
Get respect
When you study the

M-R-N-A.
(Study the)
M-R-N-A.
It can run on a gel,
And it blots really well.
Itâs the way that you get
Your next paper in Cell.

M-R-N-A.
M-R-N-A.
M-R-N-A
M-R-N-A......

In a flash, I understood where BC gets his poetic talents.

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More like this

It's been a while since I've written about mRNA and mRNA export. There has been lots of CPEB papers (cytoplasmic polyadenylation element binding protein), but nothing fundamentally new at the molecular level.
Well the latest paper from the Reed lab (squeeking into Cell on its last issue of 2006) demonstrates that the cap is indeed promoting nuclear export of mRNA in vertebrate cells.
Yes this is the surprising result interpretation of Jonathan Weissman's paper in Science.
See this entry for background on inositols. Inositol-6-phosphate (aka Inositol hexaphosphate, phytic acid, phytate) is a strange compound.

Bwahahaha!

Ok, I'll take that. RNA people are wierd and fun.

Was that you dancing with Olke Uhlenbeck et al in Banff?
Nothing like some sweet BTO covers to get your boogie going...
/rolls eyes but wouldn't trade it for a suit and tie for anything

This reminds me of "The house the rising sun"...

There is a lab in Anantomy
The lab of XXXXXXsen
It's been around for a thousand years
Yet the cap they have not found ...

;)