Chromosomes, X and Y

i-c391e5995011d135267ae80c0253f87d-somebuzz.jpg

On Neurotopia, Scicurious offers a refresher course on mitosis. This vital process occurs every time a cell divides, as centrosomes pull apart replicated chromosomes with microtubules. Normal cell mechanics limit this "molecular tug of war" to about 50 iterations, meaning we can't keep splitting chromosomes forever. But we can use meiosis make some babies. On Gene Expression, Razib Khan explains that the X chromosome is relatively scarce since males only carry one copy of it, while all other chromosomes travel in pairs. This makes the X chromosome "more susceptible to stochastic fluctuations in frequency such as random genetic drift," causing it to exhibit "greater between population variance" than the genome as whole. And on Not Exactly Rocket Science, Ed Yong stands up for X's puny boyfriend the Y, a chromosome that once jettisoned "around 97% of its original genes." These days, the human Y chromosome is definitely up to something, having racked up 310 million years worth of evolutionary change in the 6 million years since chimps and humans shared a common ancestor.

Links below the fold.

More like this

Sex chromosomes are cool. Because they're cool, I've written about them before. It's cool to trace the origins of sex chromosomes. It's cool to study how they evolve.
A few weeks ago PNAS published a paper on the evolution of snake sex chromosomes. The authors compare snake sex chromosome evolution with that of mammals and birds.
Our genes are arrayed along 23 pairs of chromosomes. On rare occasion, a mutation can change their order. If we picture the genes on a chromosome as
A few months ago I wrote the following: