Two interesting papers, one which relates KITLG and cancer, and another which connects ABCC11 and cancer. These are familiar genes. KITLG has been implicated in depigmentation, both of skin and hair. ABCC11 in earwax form and body odor. If you knock around a gene there is a high probability that you'll perturb multiple traits. Somethings the relationship between variation on a gene and pathology is more straightforward. Some of the genes responsible for normal human variation in pigmentation were originally of interest due to their implication in albinism, which is a disease with some non-trivial health consequences.
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Yoshiura K, Kinoshita A, Ishida T, Ninokata A, Ishikawa T, Kaname T, Bannai M, Tokunaga K, Sonoda S, Komaki R, Ihara M, Saenko VA, Alipov GK, Sekine I, Komatsu K, Takahashi H, Nakashima M, Sosonkina N, Mapendano CK, Ghadami M, Nomura M, Liang
Dienekes points me to a new paper, Japanese Population Structure, Based on SNP Genotypes from 7003 Individuals Compared to Other Ethnic
It's hard sometimes when you're out of synch with the rest of the world.
I've been getting queries about the ear wax paper...below the fold I've copied table 1, which shows the frequencies of the haplotypes in va