I'm away in California - while I'm gone, I'm reposting all these old entries on microscopy, enjoy!
Here's a micrograph of a fibroblast (connective tissue cell) adherring to fibronectin coated coverslip. The cell was immunostained for regular microtubules (red) and modified detyrosinated microtubules (green, although since these are only partialy modified red+green = yellow).
More like this
OK this post was a warm up for today.
The Cytoskeleton. Now that's what you call a misnomer. It is one of the most fascinating, yet misunderstood, macromolecular assemblies of the cell.
There's a new paper in Dev Cell with a nice reconstruction of a fission yeast cell (S. pombe) with all its microtubules.
From the abstract:
In this day, some biologist have to move beyond the simplistic view that the cell is a bag of M&Ms. What do I mean by that? It's the idea that enzymes and organelles are free floating entities within the cell.
Nice. Got a hi-res version?
Cool. Looks like one of those UV pics of the Sun - with solar flares & all!
Could we get a high-res image??
Sure, when I get back east (next week) I'll dig through my files and get the original.
Thanks. Look forward to it.
Looks fantastic as my new wallpaper. Thanks again.
I'll have to dig through my old CDs to find the original pic. Glad you like it.